| abstract |
The present invention relates to a composition for preventing, treating or ameliorating obesity, which comprises a biotransformed prodrug extract, wherein the composition comprising the biotransformed prodrug extract inhibits the differentiation of adipocytes and inhibits the mRNA of PPARγ or C / EBPα It has an effect of inhibiting protein expression. In addition, the composition reduced intracellular lipid accumulation and decreased body weight, liver weight, or weight of fat tissue, resulting in an excellent anti-obesity effect as compared with general progenitor extracts. Accordingly, the biologically-transformed prodrug extract of the present invention is expected to be used as a pharmaceutical composition for preventing, treating, or ameliorating obesity and a health functional food. |