| abstract |
The present invention relates to a cell sheet for gene transfer, and the cell sheet according to the present invention can be utilized as a local gene delivery system, unlike a cell sheet used for conventional tissue regeneration. In particular, when a virus is used as a gene delivery system, the virus can be propagated in the cell sheet, and the virus acts locally only at the therapeutic site, so that the virus dose Even if it is significantly lowered, it is excellent for prevention or treatment of cancer, prevention of cancer recurrence or cancer metastasis, and especially treatment of multifocal benign tumor. |