http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190076333-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3d4e15b7ef487e9eb030be8b20717a6b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6a10aeee8d52862783f7bf7b7391bc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38f20cbb2577906eb6550e4eba04c038 |
| publicationDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20190076333-A |
| titleOfInvention | Pharmaceutical composition for inhibiting cancerous metastasis containing anti-STAT3 bispecific antibody having cell penetrating ability |
| abstract | The present invention relates to a pharmaceutical composition for inhibiting cancer metastasis comprising an anti-STAT3 bispecific antibody having intracellular penetration ability as an active ingredient. The STAT3 / DNA bispecific antibody according to the present invention can overcome limitations of an antibody drug targeting only proteins existing outside the cell by including a DNA binding site that penetrates into cells and specifically binds to DNA in the nucleus. , It could be specifically bound to the phosphorylated activated form of STAT3 alone to inhibit its transcription factor activity. As a result, it could be effectively used for the development of drugs capable of inhibiting cancer metastasis progressed by activation of STAT3 . |
| priorityDate | 2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 296.