abstract |
The present invention includes compounds of formula I: (I) In this formula, Z 4, Z 7, Z 9 , Z 11, Z 22, Z 23, Z 26, Z 30, Z 34, Z 35, p, m, n, q, and cross-linking (BRIDGE) is defined in the specification . The present invention also relates to pharmaceutical compositions and methods for their use. The novel compounds are particularly useful for preventing, treating or ameliorating diseases and disorders such as obesity, type 2 diabetes, metabolic syndrome, insulin resistance, and dyslipidemia. |