| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02ad4c9403364a2277dc906d5bc5642e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70532
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70503
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate |
2018-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abc27315b0191aba77fd55507e35bbdf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37e28d5faf4c724f170c9e704ca79899 |
| publicationDate |
2019-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20190072466-A |
| titleOfInvention |
PD-L1 binding peptide and use thereof |
| abstract |
The present invention relates to a peptide which binds to PD-L1 and its use in cancer immunotherapy and anticancer therapy. The peptide of the present invention specifically binds to PD-L1 and inhibits it, thereby activating immune cell function against cancer cells, Effect. The peptides of the present invention were prepared by screening two types of peptides (PD-L1Pep-1 and PD-L1Pep-2) that bind well to human PD-L1 protein highly expressing cells using phage peptide display technology , Confirming that it binds to PD-L1 of human and mouse to inhibit its function. The peptide of the present invention showed a similar level of effect to the antibody and is relatively stable in the blood, indicating high possibility as a cancer immunotherapeutic drug in the future. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023121103-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022035222-A1 |
| priorityDate |
2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |