abstract |
The present invention provides a dermal filler comprising a hyaluronic acid-based hydrogel. The hydrogel is a coacervate formed through ionic interaction between an anionic polysaccharide (e.g., hyaluronic acid) and a cationic polysaccharide (e.g., chitosan). Dermal fillers are useful for enlarging soft tissues, reducing soft tissue defects, and improving skin quality. |