| abstract |
The present invention relates to a method for producing pluripotent stem cells (PSCs) or neural stem cells (NSCs), embryonic fibroblasts (FBs), conditioned medium, which are cells isolated from avian eggs, The present invention relates to a medium composition for cell proliferation, skin regeneration and wrinkle improvement, which comprises as an active ingredient an edible cell-conditioned medium as an active ingredient. More specifically, egg cell-conditioned medium can essentially prevent contamination due to use of animal serum, Since it exhibits various cell proliferation effects including human stem cells and skin cells and exhibits significant skin regeneration or wrinkle reducing effect without the possibility of transmission by heterologous infectious substances due to use of supporting cells, A culture medium for cell proliferation, and a cosmetic composition for skin regeneration or wrinkle improvement. |