| abstract |
The present invention provides an efficient method for synthesizing a fatty acid-peptide showing skin wrinkle-improving activity. It was confirmed that the peptide of the present invention inhibits MMP-1 expression in skin cells, promotes collagen production, exhibits skin wrinkle-improving activity, and promotes skin cell proliferation. In addition, And the peptides of the present invention are excellent in stability and skin irritation. Furthermore, the fatty acid peptides show higher skin permeability than the general peptides. The present invention provides a cosmetic composition for improving skin wrinkles comprising a fatty acid-peptide. |