| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0cefd36077e05d57ff9fca9250d762e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
| filingDate |
2017-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1ceee131973d245fddffcded8fdf71d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2aad94d7c448c278fd1116e6cf5bcd5a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f87ee1f1d3d1a1f3b7ad64b240c6e26 |
| publicationDate |
2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20190059389-A |
| titleOfInvention |
Pharmaceutical composition for preventing or treating sepsis and colorectal cancer comprising Toxoplasma gondii-GRA8 recombinant protein as an active ingredient |
| abstract |
The invention Toxoplasma gondii GRA8 (Toxoplasma gondii dense granule antigen 8) pharmaceutical composition for preventing or treating sepsis or colon cancer comprising an antigen-derived recombinant protein as an active ingredient. The toxoplasmosis ( Toxoplasma gondii- derived recombinant GRA8 protein interacts with SIRT3 in mitochondria via PKCa and deacetylates ATP5A1 to promote mitochondrial biosynthesis and activity, resulting in sepsis due to multifunctional infection, The present invention can be effectively used as a therapeutic agent for sepsis and colorectal cancer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11492376-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210082054-A |
| priorityDate |
2017-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |