http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190052372-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff283c7d6797987f01db547f606e6b32 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-357 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10 |
filingDate | 2017-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4552de0d6171b7a3e258bec729d4e12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_832691edc7cfeb66bc42a53209fb1910 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be8d5d663926c75b0223a7c0facd9d66 |
publicationDate | 2019-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20190052372-A |
titleOfInvention | Inhibitor of protein modification products formation, preparation method thereof and pharmaceutical composition for use in preventing or treating kidney disease containing the same as an active ingredient |
abstract | The present invention relates to a protein reformate inhibitor, a method for producing the same, and a pharmaceutical composition for preventing or treating renal disease containing the same as an active ingredient. The protein modification product inhibitor (DPHC) The activity of glyoxalase is enhanced to accelerate the degradation of MGO (methylglyoxal), which is a precursor of AGEs, and a significant activity increase in the Nrf2 pathway. As a result, A pharmaceutical composition for preventing or treating diabetes mellitus, diabetic nephropathy, renal failure, renal injury caused by toxin, oxygen free radical mediated kidney disease or nephritis, or a health functional food composition for improvement. |
priorityDate | 2017-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 197.