http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190048133-A

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filingDate 2017-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20190048133-A
titleOfInvention Composite hydrogel for cell encapsulation comprising collagen and silk fibroin, and manufacturing method thereof
abstract The present invention relates to a process for producing a complex hydrogel for cell encapsulation comprising collagen and silk fibroin, which comprises a step of mixing gelatin with collagen having an? -Helical structure and silk fibroin having a? -Sat structure, To a complex hydrogel for cell encapsulation. The complex hydrogel of the present invention exhibits a stiffness of 0.05 kPa to 40 kPa suitable for most tissues, which enables cell encapsulation, assists in cell adhesion and proliferation, inhibits contraction by cell traction, It can have long-term beneficial effects on tissue engineering.
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