| abstract |
A compound of formula I , or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, is an inhibitor of TrkA kinase and is also an inhibitor of TrkA kinase such as pain, cancer, inflammation, neurodegenerative disease, ≪ / RTI > are useful in the treatment of diseases which can be treated with an inhibitor: Wherein, R 1, R 2, R a, R b, R c, R d, X, Y, B and ring C are as defined herein, YB moiety with NH-C (= X) The -NH moiety is in a trans-stereomorphic form. |