| abstract |
A core composition comprising compound (I) and / or a pharmaceutically acceptable salt thereof; A sub-coating layer for coating the core composition comprising polyvinyl alcohol and / or hydroxypropyl methylcellulose; And an enteric coating layer encapsulating the subcoat layer and the core composition, wherein the subcoat layer comprises at least one polymer selected from acrylic acid / methacrylic acid / ethacrylic acid homopolymer and copolymers thereof, cellulose derivatives and polyvinylpyrrolidone , A modified release formulation such as a modified release solid oral dosage form, and a method of administering a Bruton ' s tyrosine kinase (BTK) inhibitor using the formulation. |