| abstract |
The present invention provides an antiviral precursor drug nucleoside cyclophosphate ester compound and application based on liver specificity transfer technology (liver transfer), and specifically relates to a compound of formula II and its isomers, pharmaceutically acceptable salts, hydrates, solvates and corresponding drug compositions to provide. The compound further binds alone or with other antiviral drugs to further protect against hepatitis B virus (HBV), hepatitis D virus (HDV) and human immunodeficiency virus (HIV) and the diseases it causes. |