Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_441f7c6829d19d1f693aa6ad677f2e8d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0038 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
filingDate |
2017-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fad65bf09a06fa60da9f14c0b1be36d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a133b7d8e964b88bd94af1212674c66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f548e6bbb03aa4bd6b24acde09884c5 |
publicationDate |
2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20190018795-A |
titleOfInvention |
Radiation sensitizer composition comprising micro RNA-30a and RNA-30b |
abstract |
The present invention relates to a radiation sensitive composition comprising microRNA-30a and RNA-30b as an active ingredient. In the present invention, microRNAs miR-30a and miR- miR-30b was expressed. The miR-30a and miR-30b decreased the expression of plasminogen activator inhibitor-1 (PAI-1) induced by high dose radiation And that the radiation resistance is suppressed. Therefore, miR-30a and miR-30b having the above-mentioned effects can be effectively utilized as a radiation therapy sensitizer composition, so that it is possible to improve the radiation treatment efficiency even at a low dose in various cancer treatments having increased radiation resistance, It is possible to reduce the adverse effects of dose radiation therapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210062186-A |
priorityDate |
2017-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |