abstract |
The crystals of L-lysine salt of [8-chloro-3- (4-chlorobenzyl) -4-difluoromethoxy-2-ethylquinolin-5-yloxy] acetic acid and having a diffraction angle 2? And the diffraction angles 2θ = 6.0 °, 11.7 °, 12.4 °, 15.2 °, 16.4 °, and 16 ° ° having peaks at the diffraction angles = 6.0 °, 10.0 °, 10.7 °, 12.1 °, 18.4 °, 19.2 ° and 20.1 °, 20.3 DEG and 22.6 DEG C. These crystals are chemically stable, excellent in thermal stability and physical properties, and suitable as pharmaceutical preparations. |