abstract |
The present invention relates to a composition for preventing or treating skin wrinkles or atopic dermatitis containing thymol as an active ingredient. The composition of the present invention increases the expression of type I procollagen protein in human dermal fibroblasts, inhibits the expression of MMP-1 and MMP-3 protein, and inhibits expression of TNF-a and IFN-r in human dermal keratinocytes IL-6, which is an inflammatory cytokine, and TARC (thymus and activation-regulated chemokine), which are specific for atopic dermatitis, can be effectively inhibited, and atopic dermatitis can be prevented and greatly improved. |