| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3584903efe1babebbd056e855a2cc2b3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4052a6494aaf363fee5f46708f1f7f93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3401ae9bb355456993530db970657ade
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2676004f0a596772b656f7f61a5147d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_349731476eb053df9bbc1f495a4adf5f |
| publicationDate |
2019-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20190017493-A |
| titleOfInvention |
Method for screening cancer markers and therapeutics for p53-nonmutational cancer |
| abstract |
The present invention relates to a method for screening cancer marker genes and therapeutic agents for p53-non-mutated cancer. In contrast to the mutation found in p53, which is a cancer-suppressing gene in most cancers, the screening method of the present invention based on the above-mentioned regulatory genes controlling the overexpression of MDM2 independently of the p53- Can effectively screen for p53-non-mutated cancer-specific anticancer agents. In addition, since the genes identified in the present invention (see Table 1) are significantly up-regulated in the p53 non-mutated cancer status, unlike the conventional cancer diagnosis was dependent on the presence of the p53 mutation, Diagnosis is possible. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111109199-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023101445-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111109199-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115161396-A |
| priorityDate |
2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |