Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0624908c7150e45bdd907be4f162057e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 |
filingDate |
2018-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b3e033d92076966a0fbff5d34c9ad71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c7588560b20c9ccd25368bbdf0cfe8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13d3925d688b3d1b3d9bf184bb9cec7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bf05f68d99d12a3bb17be1a15e1535a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94d9363b989325203d51f751e2df7ad8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef66c24e63da89ba39c96f79d69e1d48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7d058a029ab51a6735bfefdd8d1a99d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a66e67455590c939eeaf24df3e33be4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9947937fa38ba25420b2dadc4b0aad7 |
publicationDate |
2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20190008155-A |
titleOfInvention |
A composition for suppressing OCT4 and use thereof |
abstract |
The present invention relates to a composition for inhibiting octamer-binding transcription factor 4 (OCT4) and a use of the same. To be specifically, the present invention relates to: a composition for removing undifferentiated cells or inhibiting the formation of a teratoma or a teratocarcinoma of a cell therapy product by using the composition; a pharmaceutical composition for preventing or treating testicular cancer; a method for removing undifferentiated cells; a method of inhibiting formation of the teratoma or teratocarcinoma; a method for manufacturing a cell therapy product; and a method of preventing or treating testicular cancer. A compound of the present invention can kill undifferentiated cells remaining in the cell therapy product by inhibiting an expression or activity of OCT4 protein. |
priorityDate |
2017-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |