abstract |
The present invention relates to a 2,4,6-trisubstituted-1,3,5-triazine compound represented by the general formula ( I ) or a pharmaceutically acceptable salt, prodrug or solvate thereof, The present invention provides the use of the compounds of the invention for the manufacture of a medicament for the treatment or prevention of diseases and disorders associated with the regulation of the protein kinase and vimentin, diseases associated with cell vacuolation, in particular cancer growth and metastasis, tissue fibrosis and atherosclerosis. (I) |