| abstract |
The present invention relates to a zein-inserted liposome, wherein the phospholipid bilayer surrounds the zein core, and contains zein which is sandwiched between the phospholipids in the phospholipid bilayer. Thus, the zein has excellent biocompatibility and is superior to conventional liposomes The stability of the dispersion is excellent even with a high concentration of the encapsulated substance, thereby enabling sustained releasing of the drug. Therefore, it is possible to solve the inconvenience caused by overdose of the drug to adjust the dosage, In addition, the present invention relates to a zein-inserted liposome which can be stably released without being rapidly destabilized even under gastric fluid conditions. |