http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180136953-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-572 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
filingDate | 2017-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92a66e552455235a5f5e675ea029c447 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_363c667375b39423d803f61db932d49b |
publicationDate | 2018-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20180136953-A |
titleOfInvention | Method for producing monomers for single-stranded nucleic acid molecules |
abstract | Equation (1) Is reacted with 6-hydroxyhexanoic acid in the presence of an additive such as 1-hydroxybenzotriazole in the presence of a condensing agent in the presence of a condensation agent, and then the resultant reaction mixture is mixed with water, an alkali metal (2) < / RTI >< RTI ID = 0.0 > Or an enantiomer thereof, and reacting the obtained compound represented by the formula (2) or an enantiomer thereof with 2-cyanoethyl-N, N, N ', N'-tetraisopropylphosphorodiamidite (3), which is a monomer for producing a single-stranded nucleic acid molecule capable of inhibiting the expression of a target gene, by reacting the target gene with a coupling activator such as a diisopropylamine tetrazole salt in a solvent, Or an enantiomer thereof can be obtained. |
priorityDate | 2016-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 178.