http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180136908-A

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filingDate 2018-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33fd60fa2c1d57baa3b1310dec0f22d9
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publicationDate 2018-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20180136908-A
titleOfInvention Pathogen detection method
abstract The present invention relates to a method for detecting mycobacterium-specific metabolites in the form of mycotolium in an in vitro biological sample comprising contacting the biological sample with a reaction buffer, nicotinamide adenine dinucleotide (NAD) and formaldehyde-dependent mycotriol dihydrogenase (FD-MDH) to prepare a reaction mixture; Reducing the NAD in the reaction mixture by interaction of the FD-MDH with a given mycobacterium-specific metabolite in the form of a mycothiol when present in a biological sample; And detecting the reduced NAD in the sample, indicative of the presence of mycotiol in the biological sample and thus a mycobacterial infection in the source of the biological sample.
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