http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180133865-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0492b93574ff21721adfc0258a606913 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-48 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 |
filingDate | 2016-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bee41368d55105bbfdcb0625dad0a841 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1729fd80e6a0b762f87a18d2173cefb9 |
publicationDate | 2018-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20180133865-A |
titleOfInvention | Application of antiplatelet thrombolytic agents for the manufacture of thrombotic thrombocytopenic purpura treatment |
abstract | The present invention relates to the application of the antiplatelet thrombolysin for the manufacture of a medicament for the treatment of thrombotic thrombocytopenic purpura (TTP). The major pathogenesis of TTP is von Willebrand factor-cleaving protease. In other words, it is inhibited by the defective expression of ADAMTS13 or autoantibodies, and the von Willebrand factor (vWF) aggregates in the body in a large amount to form a plurality of superpriming polymorphs, which induces pathological platelet aggregation to form a thrombus, TTP. The antiplatelet thrombolytic agent inhibits platelet adhesion and aggregation to restore platelet, erythrocyte, and hemoglobin levels, and decreases lactate dehydrogenase levels to effectively reduce thrombocytopenia and mitochondrial hemolytic anemia. Achieve the purpose. |
priorityDate | 2016-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 226.