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filingDate 2016-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba1444712be7b49b97df81a44bda2208
publicationDate 2018-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20180132805-A
titleOfInvention Spleen tissue microarray and manufacturing method
abstract The spoloid tissue microarray comprises an array of tissue spheroids embedded in a porous mold. The product can be impregnated and segmented with wax or resin, and includes sphere that is precisely located on a regular geometric grid. A method of making a spleoid tissue microarray comprises the steps of: forming a mold of a porous material from a liquid mold material in a casting mold, and curing the liquid mold material; Removing the porous mold from the casting mold; Topping up said porous mold with an additional liquid mold material, and forming a recess in the surface of said mold by drawing in said liquid mold material due to shrinkage when said liquid mold material is cured; Disposing tissue spheroids in the recesses of the porous mold surface; And capping and sealing the tissue spheroids in the mold with a liquid mold material and curing the liquid mold material. An alternative method comprises the steps of: forming a mold of a porous material from a liquid mold material in a casting mold; Curing the liquid mold material; Removing the porous mold from the casting mold; Disposing a spleoid in a recess of a well base in the mold of the porous material; And sealing the sphere in the porous mold with additional porous material on top of the sphereoid, wherein the recesses of the well bottom portion of the porous material have additional nipple-shaped, As shown in Fig.
priorityDate 2016-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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