http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180121060-A

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filingDate 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edaa4ea9eab2c847f3bba23af0b856d6
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publicationDate 2018-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20180121060-A
titleOfInvention Once-daily fixed-dose combination capsule formulations comprising sustained release cilostazol and immediate release statin minitablets and preparation method thereof
abstract The present invention relates to a once-daily oral capsule preparation containing a fixed-dose cilostazol-releasing and statin-releasing mini-tablet, and a process for preparing the same, wherein the cilostazol-releasing mini-tablet comprises Certain fixed quantities of residual gum and ethylcellulose or Ethylcellulose and Eudragit RL or RS were used, statin general release mini tablets were prepared by high shear wet granulation method using immediate release additives and then filled into gelatin hard capsules to obtain fixed dose cilostazol and statin , It is possible to provide a composite capsule capable of oral administration once a day. Therefore, it is possible to provide a combination preparation for an elderly patient in which ischemic complex vascular disease accompanied by hyperlipidemia is frequent, and a combination preparation for patients suffering from diabetes, chronic cardiovascular disease and kidney disease It can be widely used, and the convenience of medication and patient compliance can be improved.
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type http://data.epo.org/linked-data/def/patent/Publication

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