| abstract |
The present invention relates to an alpha-helical peptide having anti-inflammatory activity and an anti-inflammatory composition containing the same. More particularly, the present invention relates to an anti-inflammatory peptide having an anti- 1, 2, 3, 4, 5, 6, 7, 8 or 9 synthesized in an amphipathic structure existing on a surface having different hydrophilicity and hydrophobicity, a novel antimicrobial active peptide consisting of the amino acid sequence shown in SEQ ID NO: 10, a novel antimicrobial active peptide synthesized with an amphipathic structure comprising lysine and arginine as is the cationic amino acid, isoleucine and tryptophan as the hydrophobic amino acid, and glutamic acid, which is an anionic amino acid, An anti-inflammatory pharmaceutical composition containing the same, It relates to medical compositions and food additives, the additive composition. The anti-inflammatory active peptide of the present invention has no cytotoxicity and exhibits excellent anti-inflammatory activity, and thus can be usefully used as an anti-inflammatory drug, cosmetic product or food preservative additive for human body. |