| abstract |
The present invention confirms that collagen synthesis is promoted without inhibiting cell growth of the peptides represented by the following formulas (1) to (4), thereby providing a cosmetic composition for improving skin wrinkles containing the peptide as an active ingredient, The present invention can be effectively used as an active ingredient of a pharmaceutical composition for external use and skin disease prevention and treatment, thereby completing a cosmetic composition. [Chemical Formula 1] [Cys-Lys-X-Lys] (2) [Lys-Val-X-Cys] (3) [Cys-Lys-X-Lys] 2 [Chemical Formula 4] [Lys-Val-X-Cys] 2 (Wherein X in the above Chemical Formulas 1 to 4 is selected from the group consisting of glutamic acid, aspartic acid, histidine, phenylalanine, alanine, cysteine, glycine, glutamine, asparagine, arginine, leucine, methionine, isoleucine, serine, tyrosine, threonine, , Proline and valine, and [] 2 may represent a dimer obtained by modifying a thiol group (-SH), which is a cysteine residue, to a reduced form (-SS-). |