| abstract |
The present invention relates to a composition for the prevention and treatment of immune diseases comprising a mixture of lactic acid bacteria and various applications thereof. The composition of the present invention is a mixture of probiotics or prebiotics in the most effective ratio and inhibits the expression of inflammatory cytokines and cartilage destruction factors in vitro or in vivo when compared to conventional anti-inflammatory agents . In addition, it has been shown that cartilage protective factor and anti-inflammatory cytokine expression is enhanced and cartilage protective effect is excellent in an animal model of immune disease, and thus it can be usefully used in related pharmacy and health functional foods industry. |