abstract |
The present invention relates to a nucleic acid complex of a novel structure capable of introducing a living nucleic acid into a cell, a composition for the diagnosis and treatment of a disease comprising the same, and a method for regulating the expression of a target gene using the same. More particularly, the present invention relates to a composition for the treatment and diagnosis of a disease comprising a nucleic acid complex in which a carrier nucleic acid complementary to a living nucleic acid and a carrier peptide nucleic acid complementarily modified to have a positive charge as a whole, and a method for regulating the expression of a target gene . |