| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d4ad61d0af1fd483d31d1c5df9b9b76 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S514-893 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0667
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 |
| filingDate |
2017-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_709f86b5ab92f46b3f9ed47d921c796a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12a9eacd85ec33cc1a6ff45940b3a65b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e95adddead9d7052fe33c444c46e560d |
| publicationDate |
2018-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20180099069-A |
| titleOfInvention |
Composition for suppressing of liver fibrosis |
| abstract |
The present invention relates to a composition for inhibiting liver fibrosis. More particularly, the present invention relates to a method of inducing thioacetamide (TAA) of a miRNA-derived stem cell culture (mi-secretome) prepared by transforming adipose-derived stem cells with a microRNA having hepatic cirrhosis inhibitory activity - inhibition of liver fibrosis. The microRNA-inducing-adipose stem cell culture medium (mi-secretome) according to the present invention can effectively inhibit liver fibrosis by inhibiting the expression of fibrosis factors associated with hepatic fibrosis and increasing the expression of anti-fibrotic factors. Therefore, it is possible to produce a microRNA-induced stem cell culture (mi-secretome) having an inhibitory effect on hepatic fibrosis by the method according to the present invention, and to effectively treat or prevent hepatic fibrosis using the mi- Can be improved. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3878432-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200074043-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023140524-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220019165-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2022515045-A |
| priorityDate |
2017-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |