| abstract |
The present invention includes novel compounds and methods for preventing or treating diseases associated with and / or resulting from overexpression and / or unregulated activity of tyrosine kinase in a subject in need thereof. In certain embodiments, the compounds of the invention include tyrosine kinase inhibitors, linkers, and ubiquitin ligase binding agents. The methods of the invention include administering to a subject a pharmaceutically effective amount of at least one compound of the invention. |