| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d4ad61d0af1fd483d31d1c5df9b9b76 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-45 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-495 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
| filingDate |
2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04b6ef8f8bc037630c6e6d1975b70459
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9b75a47608e5e42c0dbf7006414b7a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61e6835dedcdea4f2bf76ee172f50e61 |
| publicationDate |
2018-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20180085698-A |
| titleOfInvention |
Chondrogenicpellet differentiation using BMP2 and TGFβ3 expression minicircle vectors |
| abstract |
The present invention relates to chondrogenic pellets differentiated from induced pluripotent stem cells (iPSCs) by transducing mini-circle vectors encoding growth factors and their uses. The chondrocyte pellet expresses the marker gene of cartilage cell more significantly than the cartilage cell induced by differentiation in the medium supplemented with the recombinant growth factor. When the chondrocyte pellet is transplanted into a damaged area of a cartilage in a living body, cartilage regeneration may be effectively induced by the differentiated cartilage cells. This is because cartilage regeneration is more effective than when a differentiated cartilage cell is implanted by adding a recombinant growth factor And thus can be usefully used as a tissue engineering treatment method for cartilage regeneration. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021241781-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200065212-A |
| priorityDate |
2017-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |