abstract |
The present invention relates to new pyrimidine and pyridine compounds which are different from those of formula (I), formula (II), formula (III), formula (IV) and formula (V), their manufacture and their use in cancer, lupus, Diseases, Sjogren ' s disease, and rheumatoid arthritis. In a preferred embodiment, the present invention describes an irreversible kinase inhibitor, including, but not limited to, Bruton's tyrosine kinase (BTK). |