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filingDate 2016-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2018-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20180071253-A
titleOfInvention Hydrogel complex depot formulation
abstract The present invention relates to a depot formulation comprising a biodegradable silica hydrogel complex incorporating a nucleotide or nucleoside analog reverse transcriptase inhibitor wherein the silica hydrogel complex comprises the nucleotide or nucleoside analog reverse transcriptase inhibitor And having a maximum diameter of &lt; = 1000 [mu] m, by itself or as a suspension, wherein the hydrogel complex is non-flowable and structurally stable Shear stress is shear-thinned when applied by injection. The invention also relates to the use of depot formulations for the treatment of chronic viral infections and for the prevention of chronic virus reinfection. The present invention also relates to a pre-filled syringe comprising said depot formulation.
priorityDate 2015-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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