abstract |
The present disclosure generally provides compounds useful for treating cancer. In some embodiments, the disclosure provides a chemically modified small molecule cytotoxin to include one or more moieties comprising a hydrophobic moiety. In some embodiments, the disclosure provides a chemically modified small molecule cytotoxin with a fatty acid-containing moiety. In some embodiments, the disclosure provides compositions such as pharmaceutical compositions comprising such modified small molecule cytotoxins and proteins. In some embodiments, the protein is albumin or albumin. In addition, the disclosure provides various uses of such compounds and compositions. |