| abstract |
A human serum albumin mutant which can be linked to a physiologically active protein to increase the stability of the protein in blood, and a protein linked thereto. The protein to be ligated is an amino acid sequence represented by SEQ ID NO: 3, or an amino acid sequence in which 10 or fewer amino acid residues are deleted and / or 10 or fewer amino acid residues are substituted, Wherein the asparagine residue at position 318 from the N terminus of the amino acid sequence and the threonine residue at position 320 are conserved between the two residues through a single amino acid residue (X) other than proline via a peptide bond A human serum albumin mutant comprising a sequence, and a physiologically active protein linked thereto. |