abstract |
In some embodiments, the present invention relates to a mutated FAD-GDH [alpha] protein, wherein the mutated FAD-GDH [alpha] protein is mutated from a wild-type first species to contain at least one point mutation and the mutated FAD- silver, Wherein each X represents the wild-type amino acid residue of the first species and n represents the number of the wild-type amino acid residues of the first species indicated by respective parentheses at that position; a) X 1 is doedoe selected from the group consisting of X, S, C, T, M, V, Y, N, P, L, G, Q, A, I, D, W, H and E, X 1 is is L, H or V, X 2 is and D; b) X 3 is selected from the group consisting of G, H, D, Y, S and X; c) X < 4 > is selected from the group consisting of S and X; And d) X < 5 > is selected from the group consisting of S and X; |