| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e77f078aa3c0f82295fd660f1d639366 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 |
| filingDate |
2016-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36fc33f1266d21bba60535d1fdf052e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40ae5f006bcfacb945095a21c61745d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fc61eb0930877abab338fde47c621c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6ac8d6b0047a443dbdb8548dbdcd56e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfc29ed8c11037ca02d31d52c147bbd8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1614e92157a980989bb469703d8bae2 |
| publicationDate |
2018-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20180039919-A |
| titleOfInvention |
Fab fragment and uses thereof |
| abstract |
The present invention relates to a Fab fragment that specifically binds to EGFR (Epidermal Growth Factor Receptor), and more specifically, (a) a heavy chain variable region (V H ) having an amino acid sequence represented by SEQ ID NO: 31; (b) a heavy chain constant region (C H1 ) having an amino acid sequence represented by SEQ ID NO: 5; (c) a light chain variable region (V L ) having an amino acid sequence represented by SEQ ID NO: 32; And (d) a light chain constant region (C L ) having an amino acid sequence represented by SEQ ID NO: 8, wherein the partial immunization sequence is added to reduce potential immunogenicity induction and improve production yield in E. coli Can be usefully used for diagnosis, prevention or treatment of cancer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200098831-A |
| priorityDate |
2016-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |