| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4aaf127397fd5f114d8bfee1628e155e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-206
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2015-8572
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate |
2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe7a18ece39ab32023a6f45a307c1bcc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c91f7014d1202958e59990f3bcf09af7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34f22717dc6ec428dc15ad223f8249f0 |
| publicationDate |
2018-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20180035504-A |
| titleOfInvention |
Methods for Producing Oncogene-Overexpressing Induced Pluripotent Stem Cells and Uses Thereof |
| abstract |
The present invention relates to a method for producing a cancer cell-overexpressing stem cell, and a use thereof, wherein the oncogenic gene-overexpressed iPS (T / M iPS) according to the present invention is a stem cell- It was confirmed that NT embryos derived from T / M iPS-like cells as well as differentiated into pseudobells successfully generated blastocysts ex vivo. Thus, the present invention provides an initial approach to the generation of transformed iPS cells and their ability to develop after NT, providing a basis for the efficient generation of transgenic iPS cells and animal models that can be usefully used in cancer research have. It can also be applied to a method for screening candidate substances for prevention or treatment of cancer. |
| priorityDate |
2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |