| abstract |
The present invention relates to implants having drug particles attached thereto. The implants according to the present invention are capable of adhering particles to the surface of the implants to impart primary roughness to the implants themselves, thereby suppressing the fibrosis reaction. As the drug is released in the body, The reaction can be inhibited. When the drug particles are released due to the release of the drug, porosity is formed from the place where the particles are embedded, and secondary roughness can be imparted, so that the fibrosis reaction can be inhibited more effectively and spherical structure can be prevented. |