| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02ad4c9403364a2277dc906d5bc5642e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S514-825 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-501
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-502 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-501
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-50 |
| filingDate |
2016-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dd2d23b3acaad0c61aebc58101003c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9583144755a13c6c8708b8251a529d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7be4682379d967c51cd7b59a44bb2b6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b470ee0bb627202b08be91e0c689c183
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a40eedeea8053086f649f128884ddd2a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1b602abe7a7e0f8e1e989526a073397 |
| publicationDate |
2018-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20180032707-A |
| titleOfInvention |
Pharmaceutical composition for prevention or treatment of inflammatory diseases containing integrin inhibitor as an active ingredient |
| abstract |
The present invention relates to a pharmaceutical composition for the prophylaxis and treatment of an inflammatory disease comprising an integrin inhibitor and more particularly to an inhibitory activity against the integrin α5β1 inhibitor of the compound represented by the formula As a result, Compounds 1 to 123 according to the present invention have an excellent effect of blocking integrin activity by inhibiting the conversion of? 5? 1 into an active form through binding of? 5? 1 with inhibitors before binding of? 5? 1 with fibronectin A pharmaceutical composition containing as an active ingredient a low molecular compound and a derivative thereof that inhibits the binding of integrin [alpha] 5 [beta] l of the present invention to fibronectin as an extracellular matrix protein can be effectively used for the prevention and treatment of inflammatory diseases . |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111991398-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022243574-A1 |
| priorityDate |
2016-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |