| abstract |
A compound of formula (I) or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate or prodrug thereof is described. here One R 3 is H and the other R 3 is an aryl group substituted with 0-3 R 3a ; R 1 , R 2 , and R 3a are defined herein. Also described are methods of using such compounds as PAR4 inhibitors for the inhibition or prevention of platelet aggregation and for the treatment of thromboembolic disorders or for the primary prevention of thromboembolic disorders. Also described are methods of using such compounds for the treatment of human papilloma virus. In addition, pharmaceutical compositions comprising at least one compound of formula (I) are described. |