abstract |
A polypeptide encoding a chimeric fusion protein and a chimeric fusion protein is provided for the treatment of a proliferative disease, an autoimmune disease and an allogeneic immune response. The chimeric fusion protein comprises a CD24 extracellular domain, an EBV-induced 3, EBI3 polypeptide subunit, and a p28 IL-27 polypeptide subunit, wherein the EBI3 polypeptide subunit and the p28 IL-27 polypeptide subunit comprise Linked by a flexible peptide linker. |