| abstract |
(I) wherein R 1 is hydrogen, C 1-10 alkyl, cycloalkyl alkyl having 3 to 6 carbon atoms in the cycloalkyl moiety and 1 to 5 carbon atoms in the alkylene moiety, And R 2 contains 1 to 4 hetero atoms selected from N, O and S and at least one carbon atom as ring constituting atoms and at least one set of adjacent ring constituting atoms has a double bond And Y is a bond to a carbon atom which is a ring constituting atom of R 2 , and R 3 , R 4 and R 5 are hydrogen, a hydroxy group, or the like, and further, a heterocycle substituted with at least one oxo group, represents, R 6a and R 6b is, represents the other hydrogen, R 7 and R 8 are, represents the other hydrogen, R 9 and R 10 are the same or different, represents an other hydrogen, X represents O or CH 2 , And Y represents C (= O)), The tautomer, stereoisomer, or pharmaceutically acceptable salt or solvate thereof of the compound is used as an anxiolytic drug, an antidepressant drug and the like. |