http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170138399-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45c0430dd45ca6c64640c228acd8a48c |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07049 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1003 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate | 2016-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a67582f69e7d07a69c5e09a3f56538d |
publicationDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20170138399-A |
titleOfInvention | Methods of producing polynucleotides using polyvalent cationic salt compositions |
abstract | Embodiments of the disclosure include methods for the production of polynucleotides. In some embodiments, the method comprises contacting a first polynucleotide composition comprising a polyvalent cationic salt to precipitate a polynucleotide salt comprising at least one polyvalent cation counterion, wherein the polynucleotide comprises at least 7 nucleoside subunits Wherein at least two of the nucleoside subunits are bound by N3'-P5 'thiophosphoramidate subunit linkages; And non-target synthetic products and reagents; And separating the polynucleotide salt from the contacted first polynucleotide composition to produce a second polynucleotide composition comprising the polynucleotide salt. In certain embodiments, the method further comprises the following steps: contacting the polynucleotide salt with a reverse phase chromatography support; And eluting a third polynucleotide composition comprising the polynucleotide from the chromatographic support. Also provided is a composition comprising a salt of a polynucleotide comprising at least one polyvalent cation counterion. |
priorityDate | 2015-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 215.