| abstract |
The present invention provides compounds of formula (I), or stereoisomers, tautomers or pharmaceutically acceptable salts thereof, wherein: These compounds are selective factor XIa inhibitors, or dual inhibitors of fXIa and plasma calichein. The present invention also relates to pharmaceutical compositions comprising these compounds, and methods of using the same to treat thrombotic and / or inflammatory disorders. (I) In this formula, all variables are as defined herein. |