abstract |
The present invention relates to the field of therapeutics. More particularly, the present invention provides a method for producing a vector for conditionally expressing one or more immunomodulators under the control of a gene expression regulating system in the presence of an activating ligand and for therapeutic use in an animal. These vectors may be provided to treat a variety of disorders, e. G., Neoplastic disorders, through direct injection or in vitro manipulated cells such as dendritic cells. |