| abstract |
The present invention provides compositions and methods relating to or derived from an anti-IGF-IR antibody. In a particular embodiment, the invention provides a full human, humanized or chimeric anti-IGF-1R antibody, an IGF-1R binding fragment, a derivative of said antibody and an IGF-1R binding polypeptide Peptide. In another embodiment, the present invention provides a method for producing the antibody, the antibody fragment, the derivative, the nucleic acid encoding the polypeptide, the cell comprising the polynucleotide, the antibody, the antibody fragment, the derivative and the polypeptide, Derivatives, and polypeptides, such as methods of treating or diagnosing a subject having an IGF-IR related disorder or condition. |