abstract |
The present invention relates to a transgenic female nematode overexpressing a fragment (Gln 5 'tRF) derived from the 5' end of glutamine tRNA, a method for producing the transformant, and a method for screening an aging-related factor using the transgenic nematode. The transgenic female nematode model provided by the present invention is an animal model in which the glutamine tRNA 5 'terminal fragment (Gln 5' tRF) is overexpressed and the senescence is suppressed. Using the model of the present invention, And can contribute to various research fields such as anti-aging drug development and aging induction screening. |